Role: In silico studies of GEB ecosystems and computer-aided design of anti-VEGF peptides and proteins.

The team at Leipzig University is led by Prof. Jens Meiler, Humboldt Professor and head of the Institute for Drug Discovery, and by Dr. Georg Künze, research group leader for Computational Structural Biology at the Institute for Drug Discovery. Their team provides expertise in molecular modeling and protein design and is responsible for the computational engineering of peptides and proteins with an VEGF-inhibiting function. The Institute for Drug Discovery is internationally recognized as a center for the development of innovative computational approaches for therapeutics design. 

Role: In silico studies for GEB Ecosystems

The Fraunhofer Institute for Cell Therapy and Immunology IZI is dedicated to translating biomedical research into clinical applications. It carries out research in collaboration with companies, hospitals, laboratories and research institutes in the fields of biotechnology, pharmaceuticals and medical technology. The institute develops, optimises and validates methods, materials and products in the fields of cell and gene therapy, drugs and vaccines, molecular diagnostics and immunodiagnostics as well as extracorporeal therapies. The institute´s expertise includes cell biology, immunology, drug biochemistry, bioanalytics and bioproduction as well as process development and automation. The Fraunhofer IZI works closely with hospitals, carries out quality tests and supports partners in the development of manufacturing processes for medical products. The aim is to develop innovative solutions at the interface of medicine, life sciences and engineering and thus facilitate the transfer of research results into clinical practice.

Role: Design and production of recombinant bacteria.

Northumbria University, located in the vibrant city of Newcastle upon Tyne, is recognized as a research-intensive institution with a strong emphasis on interdisciplinary research. The university fosters a dynamic research environment where scholars from various disciplines collaborate to address complex, real-world problems. This interdisciplinary approach allows for innovative solutions and advances in knowledge that transcend traditional subject boundaries. Northumbria University is known for its impactful research, which has gained international recognition across various fields. It maintains strong partnerships with industry, government, and other academic institutions worldwide, enhancing the reach and application of its research outcomes. By prioritizing interdisciplinary collaboration, Northumbria University continues to be at the forefront of addressing the challenges of the 21st century, making significant contributions to knowledge, society, and policy.

Role: Dissemination, Technology transfer

Alien, specialized firm in project consulting, management, and fundraising, will spearhead the consortium's communication endeavours. Their role encompasses establishing the project's official website, crafting compelling short videos to highlight innovation impacts, orchestrating social media engagement and press releases, coordinating participation in top-level conferences and workshops, and providing comprehensive reporting on communication outcomes to the EIC.

Role: In vitro studies of the dynamic behavior of ecosystems.

ResQ Biotech is a spin-off company of the National Hellenic Research Foundation (NHRF), which was founded in 2019 and is based in the Patras Science Park, Greece. The main activity of the company consists in the discovery, preclinical development and commercial exploitation of potential therapeutic molecules against diseases caused by problematic protein folding, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.